IFNG and neoplasm: For the five tumors with HLA-A11 expression (the 4432 organoid, Panc-1 and the three tumor lines stably transduced with HLA-A11) where IFN-g release data could be obtained, the level of KRAS G12D expression correlated with their degree of recognition by this TCR, quantified by amount of IFN-γ secretion (R2 = 0.9916, p < 0.0001) (Fig. 6b).