To infer tumor purity and stromal and immune cell admixture in gliomas (Figure 10I–10P), ESTIMATE algorithm was employed to attain the outcomes, which exhibited that the stromal, immune, and ESTIMATE scores of the matrix of the expression group with high expression of TRIM5/21/22/28/34/47 are higher than those with low expression of TRIM5/21/22/28/34/47, while the three scores of the expression group with high expression of TRIM17 are lower than those with low expression of TRIM17, showing an opposite trend again. Here, TRIM5 is linked to central nervous system cancer.