Results demonstrated that TRIM5(AUC = 0.938)/17(AUC = 0.829)/21(AUC = 0.934)/22(AUC = 0.867)/24(AUC = 0.990)/28(AUC = 0.898)/34(AUC = 0.949)/TRIM47(AUC = 0.951) exposed excellent accuracy in gliomas. This evidence concerns the gene TRIM5 and glioma.