At the same time, through GEPIA2, we discovered that the mRNA expression of TRIM5/21/22/24/28/34/47 was significantly up-regulated in different LGG and GBM histological subtypes (Figure 3A, 3C–3I, 3K–3P), while the expression of TRIM17 was down-expressed in diverse gliomas subtypes (Figure 3B, 3J). This evidence concerns the gene TRIM5 and central nervous system cancer.