Its function mechanism has been well characterized in the rice blast fungus, in which the Ste50 homolog Mst50 protein directly interacts with the Mst11 kinase of the Pmk1 pathway responsible for the formation of the infection structure, the Bck1 and Ssk2 kinases in the Mps1 pathway responsible for the cell wall stress response, and the histidine kinase Hik1, which functions upstream of Osm1 and is involved in high-osmotic regulation [30,72]. This evidence concerns the gene IFT172 and infection.