S1PR2 and hearing loss disorder: The 19p13 region is home to several hearing loss loci, including DFNB15/72/95 (GIPC3) [71,72], DFNB68 (S1PR2) [73], DFNB81/Perrault syndrome (CLPP) [71,74], as well as the autosomal dominant DNFA57 locus (gene unknown) [75].