The HOXB-AS3(0.523) and HOXB-AS3(0.522) transcript variants (Figure S4B) were co-localized with the HOXB5 and HOXB6 genes, and perhaps the less prominent increased expression of the HOXB5 and HOXB6 genes was related to this fact, whereas the HOXB8 and HOXB9 gene regions showed no anti-sense RNA according to annotated data and, namely, HOXB8 and HOXB9 genes had the highest level of transcription in the HOXB locus at the NPC and TDN stages in relation to PD patients. Here, HOXB5 is linked to nasopharyngeal carcinoma.