Indeed, visceral fat is greater in patients with HFpEF than that in non-HF controls, and HFpEF is related to activation in inflammatory markers such as tumor necrosis factor (TNF)-α, interleukin-6 (IL-6), and C-reactive protein (CRP) [6,7,8,9,10,11,12]. The gene discussed is CRP; the disease is hydrops fetalis.