SMARCB1 and epithelioid sarcoma: In recent years, researchers have discovered that the SMARCB1 gene is located on chromosome 22 and, when it is altered, SMARCB1 expression is decreased or even absent [78], and a series of tumors are rapidly developed, such as malignant rhabdoid tumors of the central nervous system, renal medullary RCC, and epithelioid sarcoma [79].