Here, we revisit two genome-wide sequencing studies performed by independent laboratories providing a novel perspective: we unified a previous report that used CHART to identify MALAT1 binding sites in MCF7 breast cancer cells [28] with an independent study performed in the same cell line evaluating the binding of the SUZ12 subunit of PRC2 to the genome [31]. The gene discussed is MALAT1; the disease is breast carcinoma.