DNMT3B and neoplasm: Among all of the genes studied, HPV16 was only associated with the expression of DNMT3B, which was significantly (F (1, 18) = 9.249, p < 0.01) higher in tumors compared to paired normal tissue, and this difference was a result of significantly (p < 0.05) higher expression of DNMT3B in the tumor tissue compared to normal tissue in HPV16(+) but not HPV16(−) tumors, as revealed by Sidak’s multiple comparison post hoc test (Figure 4C).