TRDMT1 and neoplasm: To obtain a more comprehensive insight into the epigenetic control of tumor aggressiveness, we performed an RT-qPCR analysis of the DNA methyltransferases DNMT1, 3A, and 3B, the DNA demethylases TET1, 2, 3, and TDG, and the RNA methyltransferase TRDMT1 in relation to tumor metastasis and invasion.