To obtain a more comprehensive insight into the epigenetic control of tumor aggressiveness, we performed an RT-qPCR analysis of the DNA methyltransferases DNMT1, 3A, and 3B, the DNA demethylases TET1, 2, 3, and TDG, and the RNA methyltransferase TRDMT1 in relation to tumor metastasis and invasion. Here, TDG is linked to neoplasm.