Lipid metabolism includes processes, such as lipogenesis and lipolysis, lipid peroxidation (when impaired resulting in lipotoxicity), fatty acid oxidation, cholesterol synthesis, and lipid absorption, suggesting that GLP-1 affects all of these processes which, when dysregulated, contribute greatly to the development or progression of NAFLD [43]. This evidence concerns the gene GLP1R and metabolic dysfunction-associated steatotic liver disease.