LHFPL7 and colonic neoplasm: To firstly investigate whether TMEM211 is also involved in the migration and invasion of colon cancer cells, two colon cancer cells (HCT116 and DLD-1) with higher TMEM211 expression compared to normal colon FHC cells and other colorectal cancer cells (SW620) (Figure S1A) were silenced by siRNA against TMEM211 (Figure 2A).