CD163 and neoplasm: The number of both iNOS+ and CD163+ macrophages was significantly higher in the tumor and peri-tumoral compartment, compared to normal pancreatic parenchyma (iNOS+ macrophages count was 5 vs. 2.5, p = 0.009; CD163+ macrophages count was 92 vs. 66; p = 0.002; respectively), as shown in Figure 4.