CSF2 and neoplasm: For example, tumors secreting different cytokines such as GM‐CSF, G‐CSF, M‐CSF, or IL6 cause systemic expansion of myeloid‐derived suppressor cells (MDSCs) that inhibit anti‐tumor T cells and NK cells (Liechtenstein et al, 2014; Gato‐Canas et al, 2015; Ortiz‐Espinosa et al, 2022).