In line with the RNA-seq data, hsa_circ_0001400 expression was upregulated in the two AMD models, while the expression of hsa_circ_0003353, hsa_circ_0095556,ALDOA,TMEM98, andSLC4A2 were downregulated (Fig. 9A–9D). The gene discussed is TMEM98; the disease is age-related macular degeneration.