We then assessed the performance of these six methods on controlling false positives by applying them to a negative control data set on PBMCs, where no cell type was reported to have significant proportion change between 8 lupus patients treated with interferon(IFN)-\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\beta$$\end{document}β and 8 control samples [4]. This evidence concerns the gene IFNA1 and systemic lupus erythematosus.