As for patients without DM (n = 853), there were no relationships between Lp(a) levels and outcomes according to the Kaplan–Meier curves, multivariable Cox regression, and RCS fits (Additional file 8: Fig. S8, Additional file 9: Fig. S9, Additional file 10: Fig. S10, Additional file 11: Fig. S11, Additional file 12: Fig. S12, Additional file 13: Fig. S13, Additional file 14: Fig. S14 and Additional file 19: Tables S5, Additional file 20: Table S6, Additional file 21: Table S7). This evidence concerns the gene LPA and diabetes mellitus.