METTL14, another important catalytic enzyme for m6A modification, has also been well established to regulate m6A modification on different LncRNAs in various cancers, including head and neck squamous cell carcinoma, oral squamous cell carcinoma, lung adenocarcinoma, colorectal cancer, renal cell carcinoma, hepatocellular carcinoma and so forth [30–38]. Here, METTL14 is linked to colorectal cancer.