Recently research revealed that YTHDF1 involved in stability and degradation of multiple LncRNAs, such as LncRNA HCP5 [87] and LncRNA DLGAP1-AS2 [88], thus participating in regulating the progression of esophageal squamous cell carcinoma and non-small cell lung cancer, respectively. Here, YTHDF1 is linked to esophageal squamous cell carcinoma.