That study found a statistically significant interaction of T2D with an intronic variant rs4402960 located at the IGF2BP2 gene (interaction P-value: 0.040) and a missense variant rs1801282 at the PPARG gene (interaction P-value: 0.036) The respective p-values for interaction for rs4402960 and rs1801282 with diabetes on colorectal cancer were not nominally significant in our GxE analysis providing limited support for those previously observed interactions. This evidence concerns the gene IGF2BP2 and diabetes mellitus.