MYDGF and metabolic dysfunction-associated steatotic liver disease: To further verify that bone marrow-derived MYDGF restoration improved hepatic inflammation, lipogenesis, and steatosis in KO mice, we injected adeno-associated viral (AAV)-MYDGF and AAV-GFP at a dose of 1 × 1012 VP into the marrow cavities of NAFLD mice, and then assessed inflammation, lipogenesis, hepatic steatosis, and metabolism.