Transplantation of WT BMCs into KO NAFLD recipients decreased the liver index, alleviated lipogenesis and hepatic steatosis, reduced macrophage infiltration, decreased the levels of inflammatory factors in isolated hepatocytes, KCs and serum (Fig. 2A–I, P < 0.001), and improved the metabolic profiles (Fig. S5, Table S5, P < 0.001). This evidence concerns the gene TBCE and metabolic dysfunction-associated steatotic liver disease.