Cultivation experiments of NB cells with PBMCs demonstrated that in the CD45+ population, monocytes in direct co-cultures with NB cells were marked by high secretion of inflammatory M1 cytokines, INFγ, TNFα, IL-1β and M2 cytokines, IL-10 and TGFβ as well as a CD163+CD86dim phenotype, in line with M2-like cultures (stimulated with IL-4 and IL-10). Here, CD163 is linked to neuroblastoma.