Moreover, myeloid cells, regardless of NB subtype, showed accessibility to AP-1 motifs and its dimers belonging to the Fos (Fos, Fosl2, Fra1/2) and Jun (JunB) families, in both promoter and distal regions, whereas NFκB and Bach1 motifs were only accessible in the distal regions. The gene discussed is JUN; the disease is neuroblastoma.