The differences between control and NB, as well as within NB subtypes, were most significant in CD14+ CD16− monocytes, marked by expression of typical M1 (CXCL2) and M2 (CD163, TIMP1, and EREG) markers, however, lacked expression of key macrophage markers (Supplementary Fig. 5b–f, Supplementary Data 7). Here, CXCL2 is linked to neuroblastoma.