GPT and metabolic dysfunction-associated steatotic liver disease: In a recent meta-analysis, Xiao et al. 103 compared the performances of FIB-4, NFS, and APRI for the diagnoses of advanced fibrosis in NAFLD patients with summary AUROCS of 0.84, 0.84, and 0.77, respectively.103 The FIB-4 (age, AST, ALT, and platelet) can be used as a guidance to define patients who need further hepatic evaluation.