Previous studies confirmed that ADAMTS1 is involved in inhibiting the proliferation, polarization and migration of tumor (Li et al., 2015; de Assis Lima et al., 2021), affecting the quality of oocytes and embryonic development potential (Yang et al., 2021b) and promoting collagen production (Toba et al., 2016). The gene discussed is ADAMTS1; the disease is neoplasm.