Systemic investigations revealed microcytic anemia with a low hemoglobin level of 10.6 g/dl, hematocrit of 33.3%, mean corpuscular volume (MCV) of 69.8 fl, and Mean corpuscular hemoglobin of 22.1 pg; her erythrocyte sedimentation rate (ESR) was 60 mm/h and C-reactive protein (CRP) was 7.6; she had normal renal function tests (RFT) and liver function tests (LFT), normal blood sugar, thyroid hormone assay, urinalysis, and chest X-ray (Fig. 1). The gene discussed is CRP; the disease is microcytic anemia.