ADIPOQ and obesity due to melanocortin 4 receptor deficiency: This review was conducted to assess the current development in the treatment strategies of AD. It attempts to analyze the use of adiponectin as a therapeutic intervention for obesity and AD. Further, it focuses on the various neuroprotective functions of adiponectin. It also discusses that an effective method for the reduction of the risk of AD is through the avoidance and treatment of obesity.