Through model construction and internal verification using the TCGA database, TSPYL5, PARVG, KCNJ15, RTN1, CTSW, HMOX1, DCAF12L1, VNN2, and ANXA1 were identified as prognostic genes for UCEC within the shared DEGs of UCEC and PCOS. Here, KCNJ15 is linked to polycystic ovary syndrome.