In summary, this study successfully developed and validated a potential marker model for UCEC and PCOS, which identified TSPYL5, PARVG, KCNJ15, RTN1, CTSW, HMOX1, DCAF12L1, VNN2, and ANXA1 as prognostic genes for UCEC. This evidence concerns the gene KCNJ15 and polycystic ovary syndrome.