Moreover, diabetes is a risk factor in both PCOS and UCEC (Lauby-Secretan et al., 2016; Patel, 2018; Liao et al., 2021), and HMOX1, RTN1, and KCNJ15 are considered diabetes-related genes (Okamoto et al., 2012; Meng et al., 2021; Meng et al., 2022). This evidence concerns the gene RTN1 and diabetes mellitus.