In addition, the discriminated metabolic pathways of the 923 DEGs were found to be involved in 29 pathways (P < 0.05), including pathogenic Escherichia coli infection, PI3K-Akt signaling pathway, NF-κB signaling pathway, cytokine-cytokine receptor interaction, etc. (Figure 7E). This evidence concerns the gene AKT1 and escherichia coli infection.