TLR7 and neoplasm: More than 40 checkpoints were correlated with TLR7 expression levels in different tumors, and it was positively correlated with COAD, LIHC, PRAD, SKCM, STAD, TGCT, and UVM. In addition, immune checkpoint molecules were upregulated with TLR7 overexpression, allowing these tumor cells to evade immune surveillance.