AKT1 and atherosclerosis: A series of highly enriched KEGG pathways, such as lipid and atherosclerosis, AGE-RAGE signaling pathway in diabetic complications, nonalcoholic fatty liver disease, MAPK signaling pathway, and PI3K-Akt signaling pathway (Figure 2(b)), was assigned to be the most promising pathways associated with GDFMD treatment of WD liver damage.