At a similar Ct threshold, Fluorecare SARS-CoV-2 Spike Protein Test Kit displayed a diagnostic sensitivity of around 90% in our cohort of unselected patients undergoing routine COVID-19 diagnostics, which would have permitted to identify the vast majority of individuals with high viral in the upper respiratory tract, who are those at the largest risk of spreading the virus in the community (i.e., the so-called super-spreaders), especially during mass gathering events [8]. Here, CHMP5 is linked to COVID-19.