HLA-A and epilepsy: Attempts have been made to develop predictors of psychiatric adverse effects to levetiracetam.13,101,102 The most recent of these showed that people who had levetiracetam-induced psychosis had an increased polygenic risk score for schizophrenia than those who did not.103 HLA-A*1101 is enriched amongst Korean epilepsy patients with psychiatric adverse events to levetiracetam.104 Genetic variation in dopaminergic activity has also been suggested as an association.102