PNPLA3 and metabolic dysfunction-associated steatohepatitis: Single nucleotide polymorphisms (SNPs) in genes, including human patatin-like phospholipase domain-containing 3 (PNPLA3), transmembrane 6 superfamily member 2 (TM6SF2), glucokinase regulator (GCKR), membrane-bound O-acyltransferase domain-containing 7 (MBOAT7), hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), are associated with NASH development and they are associated with regulation of hepatic fat content, plasma liver enzyme levels and glucose metabolism (116, 117).