Although it has been reported that PP2A interact with cofilin-1 to induced its dephosphorylation in lung carcinoma cell line A549 (Oleinik et al., 2010), we were unable to demonstrate any direct cofilin-1-PP2AC interaction, suggesting that the interaction in ECs may be weak or indirect or this interaction could be cell type dependent. This evidence concerns the gene PPP2CA and lung carcinoma.