TFR2 and acute myeloid leukemia: However, in subjects with myelodysplastic syndrome, acute myeloid leukemia, and GBM, the higher transcription levels of TFR2 were connected to a better prognosis than that in the lower group (Calzolari et al., 2010; Di Savino et al., 2017; Nakamaki et al., 2004).