The detection of Aspergillus specific IgE and total IgE aids in the diagnosis of allergic aspergillois and can be used to differentiate allergic bronchopulmonary aspergillosis from Aspergillus sensitized asthma (e.g., IgE against Asp f1-f4), with IgG levels potentially higher in patients with Aspergillus bronchitis (e.g., IgG against Asp f1 and f2) [74]. Here, IGHE is linked to asthma.