IKZF1 and lymphoma: Our approach has led to the identification of the iTAG system a combination of DCD23 a 7 kD tag, with a chimeric degron containing sequences derived from Ikaros and ZFP91 and the molecular glue, CC220 (Iberdomide), a potent thalidomide analogue discovered for its activity in lenalidomide-resistant lymphoma cell lines.53