Variants in genes encoding potassium channels induce different forms of epilepsy, ranging from benign familial neonatal seizures (KCNQ2/3, encoding KV7.2/3) (4, 5) to severe developmental and epileptic encephalopathies (KCNA2, encoding KV1.2) (6, 7). Here, KCNQ2 is linked to Epileptic encephalopathy.