CRP and delirium: Moreover, the same study showed that after adjusting for confounding variables, including age, sex, Acute Physiology and Chronic Health Evaluation II (APACHE II) score, intubation, living alone, physical restraint, alcohol consumption, smoking, type of medical condition, and hospital length of stay before ICU admission, in a logistic regression model, elevated CRP remained an independent predictor of delirium (odds ratio, 1.07; 95% confidence interval, 1.01–1.15) (65).