Viral entry into cells mediates the downregulation of ACE2 and its consequent failure to convert the angiotensin II into angiotensin 1-7, resulting in the accumulation of angiotensin II and overstimulation of RAAS that ultimately causes hypertension, electrolyte unbalancing, lung fibrosis and inflammation, vasculitis, thromboembolism and intravascular disseminated coagulation (207, 249). This evidence concerns the gene AGT and Thromboembolism.