The flavonoids quercetin (276), naringin (277), apigenin (278, 279), luteolin (280), present in different vegetables and fruits, and the alkaloid piperin (281) and S-1-Propenylcysteine (286), are other examples of natural compounds able to increase IL-10 levels and exert antioxidant, anti-inflammatory, immunomodulatory, anti-cancer and antimicrobial properties (268, 274, 280, 294). The gene discussed is IL10; the disease is cancer.