Moreover, in the patients with higher circulating levels of IFN-γ there was a significantly higher level of soluble IL-12p40, an important Th1-like cytokine indicating that these patients may have an already primed and ongoing anti-tumour immune response (Figure 3M, 252.6 ± 32.2 vs. 163.9 ± 15.43 pg/ml, p=0.04). The gene discussed is IFNG; the disease is neoplasm.