To determine if Muc2 and Fcgbp are coordinately regulated in an animal model of UC, Muc2+/+ and Muc2-/- littermates were given DSS in their drinking water to induce colitis and proximal colonic tissues were collected for RT-PCR and Western blot analysis from days 0 to 15 post-DSS as previously described (26, 60). The gene discussed is FCGBP; the disease is colitis.