AFP and hepatocellular carcinoma: Moreover, three factors were strongly related to OS in HCC patients with HRRFs: AFP ≥ 400 ng/mL (HR: 2.91, 95% CI: 1.19-7.11, P = 0.019), satellite nodules (HR: 2.76, 95% CI: 1.05-7.22, P = 0.039), and PAT (HR: 0.18, 95% CI: 0.06-0.54, P = 0.002) (Table S3).