We transfected the four destabilized (des) clones (desARE3’UTR ERBB2-1, desARE3’UTR ERBB2-2, desARE3’UTR ERBB2-3, desARE3’UTR ERBB2-4) and desARE3’UTR ERBB2-30 into non-small-cell lung cancer cells that carry mutation in the EGFR T790M but expresses ERBB2. Here, EGFR is linked to non-small cell lung carcinoma.