SPCS1 and Alzheimer disease: These have generated a considerable amount of data that have been made available through both general and AD-dedicated databases such as Accelerating Medicines Partnership-Alzheimer's Disease (AMP-AD) (Hodes and Buckholtz, 2016) and many genes and pathways that may play crucial roles in AD have been identified [e.g., YAP1 (Xu et al., 2018) & SPCS1 (Patel et al., 2019)].