Although Tac and the pan‐HDACis (SB and SAHA) treatment counteracted the enhanced ER‐Ca2+ accumulation in 3xTg‐AD hippocampal neurons (Figure 2c), no differences were found on HT22 ER‐Ca2+ levels in the presence of AβO plus pan‐HDACis (Figure S2G). Here, ABO is linked to Alzheimer disease.