For instance, SCD is a single gene mutation induced anemia disease, where the Glu6Val mutation results in an abnormal appearance of hemoglobin B (HbB) rather than hemoglobin A (HbA).[97] Autografting patients with CRISPR‐corrected hematopoietic stem cells (HSCs) have been shown to increase the number of corrected HSCs by fivefold 16 weeks after planting, with 45% of red blood cells having at least one HbA allele. Here, HBB is linked to Schnyder corneal dystrophy.