Sixteen weeks after SCD mice receiving edited HSPCs, the blood cell lysates experiments revealed that mHbB presented 79% of total HbB and the hematologic parameters test also reflected that the red blood functions were almost improved (86%).[149] Similarly, base editors have also been used to correct the point mutation of HGPS, where the progerin is caused by the C to T substitution (c.1824) in the LMNA gene. This evidence concerns the gene HBB and Schnyder corneal dystrophy.