APOB and obesity due to melanocortin 4 receptor deficiency: Participants in the current study had markedly elevated ApoB48, a specific marker of chylomicron particles, at baseline (median range of 2.60–4.90 mg dl−1) compared with healthy participants (median, 0.51 mg dl−1), hyperlipidemic participants (median, 0.7 mg dl−1) and participants with obesity (median, 0.82 mg dl−1), putting them at an increased risk for developing acute pancreatitis46.