CASP1 and familial dilated cardiomyopathy: For example, Zhou et al.12 reported that lncRNA myocardial infarction–associated transcript (MIAT) functions as a competing endogenous RNA to up-regulate DAPK2 by sponging miR-22-3p in DCM; Feng et al.13 found that lncRNA DCM-related factor (DCRF) regulates cardiomyocyte autophagy by targeting miR-551b-5p in DCM; Yang et al.14 demonstrated that lncRNA, Kcnq1ot1, is over-expressed in DCM, and silencing Kcnq1ot1 inhibits pyroptosis by regulating miR-214-3p and caspase-1 expressions.