Additionally, among 5 genes related to myocardial repair in mice (Hdac4, Mesp1, Ngf, Pim1, and Yap1), Ngf and Pim1 were significantly down-regulated, implying a decreased repair ability of cardiomyocytes in DCM and suggesting a potential treatment target to restore repairment in DCM. This evidence concerns the gene YAP1 and familial dilated cardiomyopathy.