Pinellia pedatisecta Schott extract (PE) promoted the expression of MHCII, CD80, CD86 and IL-12, the proliferation of CD4+ and CD8+ T cells, and induced the differentiation of IFN-y+CD4+ and GZMB+CD8+ T cells in tumor-associated dendritic cells (TADC). Here, CD8A is linked to neoplasm.