SN-011 maintains STING in an inactive form, which inhibits the induction of interferon and inflammatory cytokines by 2′3′-cGAMP, herpes simplex virus type 1 infection, Trex1 deficiency, overexpression of cGAS-STING, and STING-associated vasculopathy with onset in infancy (SAVI) mutation (Hong et al. 2021). The gene discussed is STING1; the disease is STING-associated vasculopathy with onset in infancy.