NPPA and cardiac hypertrophy: STING knockdown in neonatal rat cardiomyocytes (NRCMs) reduced mRNA levels of cardiac hypertrophy markers, such as atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP), which were increased by angiotensin-II (Ang-II) treatment (Zhang et al. 2020).