Immunofluorescence staining showed that CLTA was extensively colocalized with Rab11a (a recycling endosomal marker) and partially within the scope of EEA1 (an early endosomal marker) and Rab7 (a late endosomal marker) in HCC cells (Fig. 3C). The gene discussed is CLTA; the disease is hepatocellular carcinoma.